Bradd Dalziell and Cale Morton are delisted by the Eagles.
"This is the toughest part of the game, particularly when it involves quality people," Eagles football operations manager Craig Vozzo said in a club statement.
"Unfortunately, it is the nature of the game.
"Both Bradd and Cale have been valued contributors to the football club and we thank them for the role they have each played. They will always be welcome at the West Coast Eagles."